منابع مشابه
Sequence Dependent Long Range Hole Transport in DNA
A guanine radical cation (G+•) was site-selectively generated in double stranded DNA and the charge transfer in different oligonucleotide sequences was investigated. The method is based on the competition between a charge transfer from G+• through the DNA and its trapping reaction with H2O. We analyzed the hole transfer from this G+• to a GGG unit through one, two, three, and four AT base pairs...
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The DNA contained in every living cell not only stores the genetic information; it functions in a complex molecular network that can condense, transcribe, replicate and repair genes. The essential role played by the sequence dependent structure and deformability of DNA in these basic processes of life, has received increasing attention over the past years. The present work aims at better unders...
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Recent single-molecule micromanipulation experiments on DNA subject to small distortion revealed positive coupling between DNA stretching and twisting--for instance, DNA elongates when overtwisted. Here we propose a method to calculate the twist-stretch coupling constant specific to a DNA fragment of a given sequence. The method employs a sequence-dependent dinucleotide force field and is based...
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This paper presents the idea of creating cells while reducing part-level sequence-dependent setup time in general cellular manufacturing systems (CMS). Setup time reduction in CMS has gained modest attention in the literature. This could be attributed to the fact that the fundamental problem in cell formation in CMS has been mainly related to material handling and machine utilization while setu...
متن کاملProbability Models for DNA Sequence Evolution
ing from the example, suppose that there are n subpopulations that have reached equilibrium sizes N1, . . . Nn and let mij be the probability that an individual in subpopulation i is a descendant of an individual in subpopulation j. That is, to build up subpopulation i in generation t + 1, we sample Ni times with replacement from generation t, picking at random from subpopulation j with probabi...
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ژورنال
عنوان ژورنال: Journal of Biological Physics
سال: 2004
ISSN: 0092-0606
DOI: 10.1023/b:jobp.0000035844.35839.60